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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COPS2 All Species: 50.3
Human Site: T134 Identified Species: 69.17
UniProt: P61201 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61201 NP_001137359.1 443 51597 T134 L L Q E F Y E T T L E A L K D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001089276 443 51433 T134 L L Q E F Y E T T L E A L K D
Dog Lupus familis XP_862009 444 51751 T134 L L Q E F Y E T T L E A L K D
Cat Felis silvestris
Mouse Mus musculus Q8BG32 422 47418 T123 W A K S E K R T F L R Q A L E
Rat Rattus norvegicus P61203 443 51578 T134 L L Q E F Y E T T L E A L K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521692 705 77929 T381 L L Q E F Y E T T L E A L K D
Chicken Gallus gallus NP_001026767 443 51677 T134 L L Q E F Y E T T L E A L K D
Frog Xenopus laevis Q6IR75 441 51318 T132 L L Q E F Y E T T L D A L K D
Zebra Danio Brachydanio rerio Q6IQT4 443 51553 T134 L L Q E F Y E T T L E A L K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q94899 444 51508 T135 L L Q N F Y E T T L D A L R D
Honey Bee Apis mellifera XP_392587 444 51537 T135 L L Q D F Y E T T L D A L K D
Nematode Worm Caenorhab. elegans O01422 495 56762 T131 L L Q H F Y E T T L D A L K D
Sea Urchin Strong. purpuratus XP_780196 444 51783 T135 L L Q E F Y E T T L M A L K D
Poplar Tree Populus trichocarpa XP_002330981 439 51362 Y128 F S L L Q E F Y Q T T L K A L
Maize Zea mays NP_001149870 438 51327 Y128 F T L L Q E F Y Q T T L K A L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W207 439 51168 Y128 T G L L Q E F Y Q T T L K A L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SI58 490 56940 K133 K A V Q C I E K F Y S L T L Q
Conservation
Percent
Protein Identity: 100 N.A. 98.6 99.3 N.A. 23 100 N.A. 53.9 99.7 98.8 99.3 N.A. 83.7 86.4 57.7 85.5
Protein Similarity: 100 N.A. 98.8 99.3 N.A. 43.1 100 N.A. 57.8 99.7 99.3 100 N.A. 91.4 93.4 72.9 92.1
P-Site Identity: 100 N.A. 100 100 N.A. 13.3 100 N.A. 100 100 93.3 100 N.A. 80 86.6 86.6 93.3
P-Site Similarity: 100 N.A. 100 100 N.A. 26.6 100 N.A. 100 100 100 100 N.A. 93.3 100 93.3 93.3
Percent
Protein Identity: 64.1 64.1 N.A. 60.5 N.A. 45.7
Protein Similarity: 80.1 80.3 N.A. 79 N.A. 65.3
P-Site Identity: 0 0 N.A. 0 N.A. 6.6
P-Site Similarity: 0 0 N.A. 0 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 0 0 0 0 0 71 6 18 0 % A
% Cys: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 6 0 0 0 0 0 0 24 0 0 0 71 % D
% Glu: 0 0 0 53 6 18 77 0 0 0 42 0 0 0 6 % E
% Phe: 12 0 0 0 71 0 18 0 12 0 0 0 0 0 0 % F
% Gly: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % I
% Lys: 6 0 6 0 0 6 0 6 0 0 0 0 18 65 0 % K
% Leu: 71 71 18 18 0 0 0 0 0 77 0 24 71 12 18 % L
% Met: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % M
% Asn: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 71 6 18 0 0 0 18 0 0 6 0 0 6 % Q
% Arg: 0 0 0 0 0 0 6 0 0 0 6 0 0 6 0 % R
% Ser: 0 6 0 6 0 0 0 0 0 0 6 0 0 0 0 % S
% Thr: 6 6 0 0 0 0 0 77 71 18 18 0 6 0 0 % T
% Val: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 71 0 18 0 6 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _